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Projektverzeichnis

3R-Models and Diseases

ALLERGY

127-11Establishing a novel system for quantitative production of murine basophils in vitro
Kaufmann T., PD Dr., Institute of Pharmacology, University of Bern, Switzerland
 
80-01Induction of a primary T cell mediated immune response against drugs and drug metabolites in vitro
Pichler, W.J., Prof. Dr., Division Allergology, University Hospital Bern, Switzerland
 
67-99Human monocyte-derived dendritic cells as in vitro indicators for contact allergic potential of chemicals
Ulrich P., Dr., PCS/GENEX-Experimental Toxicology, Novartis Pharma AG, Basel, Switzerland
 

ANGIOGENESIS

139-14An in-vitro microvascular model of the endothelial barrier
Herrmann, M., Dr., AO Research Institute Davos, Switzerland
 
117-09Embryonic stem-cell-derived in-vitro model of tissue inflammation following confrontation with implant materials
Wartenberg M., Prof. Dr., Friedrich Schiller University Jena and Justus Liebig University Giessen, Germany
 
76-01Development of a model of heart angiogenesis in vitro
Battegay E., Prof. Dr., Outpatient Department of Internal Medicine and Department of Research, University Hospital Basel, Switzerland
 

ARTHRITIS

68-99Genetic analysis of a 3D in vitro model of the rheumatic pannus tissue
Illges H., PD Dr., Biotechnologie Institut Thurgau an der Universität Konstanz, Switzerland
 
62-97Development of an in vitro model system for cartilage invasion by synovial fibroblasts
Gay R. E., Prof. Dr., Department of Rheumatology, University Hospital Zürich, Switzerland
 
50-96Morphometric Analysis of human articular cartilage
Hunziker E., Prof. Dr., M.E.Müller Institut für Biomechanik, University of Bern, Switzerland
 

ASTHMA

82-02Magnetic Resonance Imaging (MRI) for the non-invasive assessment of lung inflammation and pulmonary function in the rat
Beckmann N., PD Dr., Novartis Pharma AG Basel Novartis Institute of Biomedical Research (NIBR), Basel, Switzerland
 

ATHEROSCLEROSIS

135-13In-vitro engineering of a human cell-based threedimensional dynamic model of atherosclerosis
Weber, B, Dr. Dr., Swiss Center for Regenerative Medicine, University Hospital Zurich, Switzerland
 
111-08Establishment of an organ ex-vivo tissue slice model for cardiovascular research in particular for therapeutic atherosclerosis targeting
Hunziker P., PD Dr., Intensive Care Unit, University Hospital Basel, Switzerland
 

BARRIER SYSTEMS IN VITRO

93-04Development of a novel multicellular 3-dimensional blood brain barrier in vitro model
Ogunshola O., Dr., Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Switzerland
 
91-04Establishment and validation of a Choroid Plexus Model to study drug transport
Fricker G., Prof. Dr., Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls Universität Heidelberg, Germany
 
65-98Reconstructed human epidermis as model for predicting irritancy
Ponec M., Prof. Dr., Skin Research Laboratory, Department of Dermatology, Leiden University Medical Center, Netherland
 

BIOACCUMULATION

141-14In-vitro alternatives to in-vivo bioconcentration-testing in fish: restricted to rainbow trout or broadly applicable ?
Segner, H., Prof., Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Bern, Switzerland
 
108-07Cultured piscine hepatocytes as an in-vitro source of metabolic clearance data that is currently gleaned by in-vivo bioaccumulation testing in fish
Segner H., Prof. Dr., Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Berne, Switzerland
 
100-06Development of an in-vitro system for modeling bioaccumulation of neutral, ionizable, and metabolically active organic pollutants in fish
Escher B., Prof. Dr., Dept. of Environmental Toxicology, EAWAG, Dübendorf, Switzerland
 

BLACKLEG DISEASE

136-13Development of an in-vitro potency assay for the Clostridium chauvoei vaccines: Replacement of the guinea-pig-challenge potency test
Frey, J., Prof., Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Switzerland
 

HETEROTYPIC INTERACTIONS

144-15Development of in vitro three-dimensional multi-cellular culture models to study the role of heterotypic interactions during colorectal carcinomatous invasive process
Rüegg, C., Prof. Dr., Department of Medicine, Chair of Pathology, University of Fribourg, Switzerland
 

FEVER

52-96Development of an interleukin-1 (IL-1) assay with rabbit blood as an alternative to the rabbit pyrogen test
Hartung T., Prof.. Dr., Biochemical Pharmacology, University of Konstanz, Germany
 

INFECTIOUS DISEASES

118-10Engineering of an in vitro hepatocyte tissue system for malaria liver infection research
Mancama D., Dr., Systems Biology, Biosciences Unit, CSIR, South Africa
 
116-09Organotypic brain-slice cultures derived from regularly-slaughtered animals as an in-vitro alternative for the investigation of neuroinfectious diseases in ruminants
Oevermann A., Dr., Vetsuisse Faculty, University of Berne, Switzerland
 
113-08Generic in-vitro evaluation assay for immunological correlates of protection to replace animal challenge infections
Summerfield A., Dr., Institute of Virology and Immunoprophylaxis (IVI), Mittelhaeusern, Switzerland
 
111-08Establishment of an organ ex-vivo tissue slice model for cardiovascular research in particular for therapeutic atherosclerosis targeting
Hunziker P., PD Dr., Intensive Care Unit, University Hospital Basel, Switzerland
 
110-08Development of an in-vitro assay for the screening of antischistosomal drugs
Keiser J., Prof. Dr., Swiss Tropical Institute, University of Basel,Switzerland
 
107-07Evaluation of an in vitro model to identify host parameters associated with virulence of Toxoplasma gondii strains
D’Souza S., Dr., Pasteur Institute of Brussels-ISP,1180-Uccle, Belgium
 
105-06Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates
Ruggli N., Dr., Institute of Virology and Immunoprophylaxis (IVI), Mittelhaeusern, Switzerland
 
99-05The NEMO network (Non-mammalian Experimental Models for the study of bacterial infections)
Cosson P., Prof. Dr., Département de Physiologie Cellulaire et Métabolisme, Centre Medical Universitaire Genève, Geneva 4, Switzerland
 
90-03A non-mammalian system to study bacterial infections
Cosson P., Prof. Dr., Centre Medical Universitaire, Dpt de Morphologie, Geneva 4, Switzerland
 

INFLAMMATION

126-11Development and validation of a model to investigate myeloid-cell homeostasis
Benarafa C., Dr., Theodor Kocher Institute, University of Bern, Switzerland
 
117-09Embryonic stem-cell-derived in-vitro model of tissue inflammation following confrontation with implant materials
Wartenberg M., Prof. Dr., Friedrich Schiller University Jena and Justus Liebig University Giessen, Germany
 
82-02Magnetic Resonance Imaging (MRI) for the non-invasive assessment of lung inflammation and pulmonary function in the rat
Beckmann N., PD Dr., Novartis Pharma AG Basel Novartis Institute of Biomedical Research (NIBR), Basel, Switzerland
 
73-00Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice
Landmann R., Prof. Dr., Division of Infectious Diseases, Department of Research, University Hospital Basel, Switzerland
 
63-97In vitro study of pathogenesis of sepsis in a conditionally immortalized Kupffer cell line
Landmann R., Prof. Dr., Division Infectious Deseases, Department Research, University Hospital Basel, Switzerland
 
62-97Development of an in vitro model system for cartilage invasion by synovial fibroblasts
Gay R. E., Prof. Dr., Department of Rheumatology, University Hospital Zürich, Switzerland
 
48-96Utilization of a model of culture of human intestinal cell lines for the study of the pathogenicity of different strains of Clostridium difficile
Kraehenbuhl J.-P., Prof. Dr., Institut Suisse de Recherches Expérimentales sur le Cancer (ISREC), Switzerland
 
46-96Development and Validation of an In Vitro Model Simulating Mechanical Ventilation-Induced Inflammation
Pugin J., Dr., Division des Soins Intensifs de Médecine, Hôpital Cantonal Universitaire, Genève, Suisse
 

IRRITATION

IRRITATION: EYE AND SKIN

65-98Reconstructed human epidermis as model for predicting irritancy
Ponec M., Prof. Dr., Skin Research Laboratory, Department of Dermatology, Leiden University Medical Center, Netherland
 

IRRITATION: SENSORY

ISCHEMIA

133-12Development of an in vitro system to grow and investigate vascular endothelial cells under physiological flow conditions
Rieben R., Prof., Department of Clinical Research, University of Bern, Switzerland
 
103-06An in vitro Model of Central Nervous System Infection and Regeneration: Neuronal Stem Cells as Targets of Brain Damage & Regenerative Therapies in Bacterial Meningitis.
Leib S.L., Prof. Dr., Institute of Infectious Diseases, University of Bern, Switzerland
 
102-06Isolated, autologous blood-perfused heart: Replacement of heterotopic heart transplantation
Bogdanova A, Dr., Institute of Veterinary Physiology, University of Zurich, Switzerland
 
76-01Development of a model of heart angiogenesis in vitro
Battegay E., Prof. Dr., Outpatient Department of Internal Medicine and Department of Research, University Hospital Basel, Switzerland
 
69-99A human neural cell line as in vitro model system for the excitotoxic cascade during stroke
Bicker G., Prof. Dr., Abt. Zellbiologie, Physiologisches Institut, Stiftung Tierärztliche Hochschule Hannover, Germany
 
64-97Use of three-dimensional brain cell cultures as a model for ischemia-related research
Honegger P., Prof. Dr., Institute of Physiology, Faculty of Medicine, University of Lausanne, Switzerland
 

LUNG DISEASES

128-11Genetic modification of the human airway epithelium – a paradigmatic system to study host responses to human respiratory viruses
Thiel V., PD Dr., Institut für Immunbiologie, Kantonsspital St. Gallen, Switzerland
 

LUNG INFLAMMATION

143-15An advanced in-vitro model of pulmonary inflammation based on a novel lung-on-chip technology
Guenat, O., Prof. Dr., ARTORG Center, University of Bern & Pneumology and Thoracic Surgery Clinics, University Hospital of Bern, Switzerland
 

MALARIA

118-10Engineering of an in vitro hepatocyte tissue system for malaria liver infection research
Mancama D., Dr., Systems Biology, Biosciences Unit, CSIR, South Africa
 

MECHANICAL STRESS

143-15An advanced in-vitro model of pulmonary inflammation based on a novel lung-on-chip technology
Guenat, O., Prof. Dr., ARTORG Center, University of Bern & Pneumology and Thoracic Surgery Clinics, University Hospital of Bern, Switzerland
 

NEOSPOROSIS

85-03Development of an in vitro culture model to generate Neospora caninum and Toxoplasma gondii oocysts and sporozoites
Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland
 
72-00Development and applications of an in vitro cultivation model for Neospora caninum tissue cyst formation
Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland
 

SEPSIS

143-15An advanced in-vitro model of pulmonary inflammation based on a novel lung-on-chip technology
Guenat, O., Prof. Dr., ARTORG Center, University of Bern & Pneumology and Thoracic Surgery Clinics, University Hospital of Bern, Switzerland
 

SEPTIC SHOCK MODELS

73-00Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice
Landmann R., Prof. Dr., Division of Infectious Diseases, Department of Research, University Hospital Basel, Switzerland
 
63-97In vitro study of pathogenesis of sepsis in a conditionally immortalized Kupffer cell line
Landmann R., Prof. Dr., Division Infectious Deseases, Department Research, University Hospital Basel, Switzerland
 

SENSITIZATION

67-99Human monocyte-derived dendritic cells as in vitro indicators for contact allergic potential of chemicals
Ulrich P., Dr., PCS/GENEX-Experimental Toxicology, Novartis Pharma AG, Basel, Switzerland
 

SENSORY IRRITATION

70-99Sensory irritant screening using a stable cell line expressing the vanilloid receptor
Baumann T., Prof. Dr., Dept. of Neurological Suregry,Oregon Health and Sciences University, Portland, USA
 

SPINAL CORD REPAIR / DISEASES

129-11The use of microfluidic chambers to study axonal transport in PTEN and SOCS3 dependent axonal regeneration
He Zhigang, Prof., Children's Hospital and Department of Neurology, Harvard Medical School, Boston, MA 02115
 
121-10Organotypic spinal cord slices to study SCI and MS like lesions
Chrast R., Prof. Dr., Department of Medical Genetics, University of Lausanne, Switzerland
 
120-10Development of non-invasive strategies to study corticospinal neuron disease, injury and repair
Jabaudon D., Prof. Dr., Dpt. of Basic Neurosciences, University of Geneva, Switzerland
 

TRANSGENIC MODELS

60-97Transgenic protozoa (Trypanosoma spp.) as an alternative to transgenic animals
Roditi I., Prof. Dr., Institutes of General Microbiology and Parasitology, University of Bern, Switzerland
 

VETERINARY DISEASE

116-09Organotypic brain-slice cultures derived from regularly-slaughtered animals as an in-vitro alternative for the investigation of neuroinfectious diseases in ruminants
Oevermann A., Dr., Vetsuisse Faculty, University of Berne, Switzerland
 
104-06Development of in vitro strategies to propagate and characterize hemotrophic mycoplasmas
Hofmann-Lehmann R., Prof. Dr., Clinical Laboratory, Vetsuisse-Faculty, University of Zurich, Switzerland
 


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